Castle Biosciences Inc. Watch

from 10-Q 5 pages Amended Participation Agreement

from 10-Q 5 pages Amended Participation Agreement

from 10-Q 5 pages Amended Participation Agreement

from 10-Q 3 pages Castle Biosciences, Inc. Non-Employee Director Compensation Policy Adopted: June 8, 2019 Amended: January 28, 2021 Amended January 24, 2022 Amended: January 31, 2023 Amended: May 31, 2024 Amended: May 22, 2025

from 10-Q 57 pages Office Lease Agreement for Two Scottsdale Landing Perimeter Gateway Portfolio LLC, a Delaware Limited Liability Company, as Landlord and Castle Biosciences, Inc., a Delaware Corporation, as Tenant

from 10-Q 2 pages Effective on March 7, 2025 , Landlord and Tenant Amend the Above-Referenced Lease as Follows. ☐ A. Leased Premises: The Suite or Unit Number Identified in Paragraph 2a(1) Is: ☐ (1) Changed to . ☐ (2) Contains Approximately Rentable Square Feet ("Rsf"). ☒ B. Term: ☐ (1) the Length of the Term Stated in Paragraph 3a Is Changed to Months and Days. ☐ (2) the Commencement Date Stated in Paragraph 3a Is Changed to . ☒ (3) the Expiration Date Stated in Paragraph 3a Is Changed to March 31, 2026 . ☒ C. Rent: The Amount of the Base Monthly Rent Specified in Paragraph 4a Is Changed To: $ 54,860.30 From 08/01/2025 to 03/31/2026 ; $ From to ; $ From to ; $ From to ; $ From to ; $ From to . ☐ D. Security Deposit: The Amount of the Security Deposit in Paragraph 5 Is Changed to $ . ☐ E. Maintenance and Repairs: The Following Item(s) Specified in the Identified Subparagraph of Paragraph 15c Will Be Maintained by the Party Designated Below: Para. No. Description Responsible Party ☐ N/a ☐ Landlord ☐ Tenant ☐ N/a ☐ Landlord ☐ Tenant ☐ N/a ☐ Landlord ☐ Tenant ☐ N/a ☐ Landlord ☐ Tenant ☐ N/a ☐ Landlord ☐ Tenant ☐ F. Parking: ☐ (1) Common Parking: The Number of Vehicles Identified in Paragraph A(1) of the Commercial Lease Addendum for Parking (Txr-2107) Is Changed to Vehicles. (Txr-2114) 07-08-22 Initialed for Identification by Landlord: /S/ Lt,___ , and Tenant: , Page 1 of 2

from 10-Q 2 pages Confirmation of Amendment Provisions

from 10-Q 3 pages Castle Biosciences, Inc. Non-Employee Director Compensation Policy Adopted: June 8, 2019 Amended: January 28, 2021 Amended January 24, 2022 Amended: January 31, 2023 Amended: May 31, 2024

from 10-Q 5 pages Name: Franklin Stokes Section 1. Eligibility

from 10-Q 6 pages Name: Derek Maetzold Section 1. Eligibility

from 10-Q 5 pages Name: Kristen Oelschlager Section 1. Eligibility

from 10-Q 5 pages Name: Tobin Juvenal Section 1. Eligibility

from 10-Q 8 pages Certain Confidential Information Contained in This Document, Marked by [***], Has Been Omitted Because It Is Both (I) Not Material and (II) Is the Type That the Registrant Treats as Private or Confidential. First Amendment to Lease Agreement

from 10-K 9 pages Second Amendment to Commercial Contract - Unimproved Property

from 10-K 36 pages Castle Biosciences, Inc. Severance and Change in Control Plan Effective Date: November 3, 2023

from 10-Q 2 pages Recitals

from 10-Q 6 pages Sixth Amendment to Standard Office Lease

from 10-Q 32 pages Commercial Contract - Unimproved Property Use of This Form by Persons Who Are Not Members of the Texas Association of Realtors®, Inc. Is Not Authorized. ©texas Association of Realtors®, Inc. 2022

from 10-Q 6 pages Fourth Amendment to Standard Office Lease

from 10-K 2 pages Commercial Lease Amendment Use of This Form by Persons Who Are Not Members of the Texas Association of Realtors®, Inc. Is Not Authorized. ©texas Association of Realtors®, Inc. 2022